QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS5-Region Domestic Shipping
What is VIP?
VIP (Vasoactive Intestinal Peptide — VPAC1/VPAC2 agonist) is a 28-amino acid neuropeptide. 28-amino acid neuropeptide activating VPAC1 (expressed broadly) and VPAC2 (expressed in pancreas, heart, lung) receptors — class B GPCRs signalling via cAMP. Produces vasodilation, smooth muscle relaxation, immunomodulation, SCN circadian pacemaker regulation, bronchodilation, and GI secretagogue effects.
Research Applications
VPAC1/VPAC2 Pharmacology
Receptor distribution, cAMP signalling, downstream effector comparison
Vasodilation Research
Vascular smooth muscle relaxation, blood flow, endothelial interaction
Circadian Biology
SCN pacemaker modulation, circadian rhythm entrainment research
Immunomodulation
Anti-inflammatory cytokine modulation, regulatory T-cell induction
GI Biology
Intestinal secretion, motility, VIPoma and GI peptide axis research
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 40077-57-4 |
| Molecular Formula | C₁₄₇H₂₃₇N₄₃O₄₁ |
| Peptide Type | Neuropeptide / Vasodilatory Peptide |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | 24 months unopened |




