QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS5-Region Domestic Shipping
What is Tadalafil?
Tadalafil (Cialis — long-acting PDE5 inhibitor (~36hr half-life)) is a Small molecule C₂₂H₁₉N₃O₄, MW 389.4. Long-acting PDE5 inhibitor (half-life ~36hr vs 4–5hr sildenafil/vardenafil). Prevents cGMP degradation in smooth muscle, sustaining NO/cGMP-mediated vasodilation and relaxation. FDA approved for ED and pulmonary arterial hypertension (PAH). High PDE5 selectivity over PDE1/3/4/6.
Research Applications
PDE5 Inhibition Biology
cGMP phosphodiesterase inhibition, NO/cGMP pathway amplification
Penile Smooth Muscle Research
Corpus cavernosum relaxation, haemodynamic studies
PAH Research
FDA-approved PAH indication — pulmonary vascular resistance models
Long-Acting PK
36hr half-life — sustained PDE5 inhibition pharmacokinetics
vs Sildenafil/Vardenafil
Duration, selectivity, and PDE isoform profile comparison
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 171596-29-5 |
| Molecular Formula | C₂₂H₁₉N₃O₄, MW 389.4. |
| Identity | MS molecular weight confirmed — every batch |
| Peptide Type | Phosphodiesterase Type 5 (PDE5) Inhibitor |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | As indicated by manufacturer |
