QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS5-Region Domestic Shipping
What is Sildenafil?
Sildenafil (Viagra/Revatio) is the first-in-class PDE5 inhibitor — selective for PDE5 over PDE6 (10×) and PDE1 (80×). Half-life ~4hr — suitable for acute response and dose-response studies. FDA-approved for erectile dysfunction and PAH (Revatio). Reference compound for NO/cGMP pathway research. CAS 139755-83-2.
Research Applications
NO/cGMP Reference Compound
First-in-class PDE5 inhibitor — foundational cGMP signalling
Acute PDE5 Inhibition
4hr half-life — acute onset/offset and dose-response kinetics
Pulmonary Hypertension
Revatio indication — pulmonary vascular resistance research
PDE Selectivity Profile
PDE5 vs PDE6 vs PDE1 selectivity — comparative PDE pharmacology
vs Tadalafil Comparison
Short-acting vs long-acting PDE5 — duration studies
Quick Specs
| Form | Tablet — 100mg per tablet, 100-tablet bottle |
| CAS Number | 139755-83-2 |
| Molecular Formula | C₂₂H₃₀N₆O₄S |
| Molecular Weight | 474.6 g/mol |
| Compound Type | PDE5 Inhibitor |
| Purity | ≥99% by HPLC — every batch |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house synthesis — Qingdao, China |
| Storage | Room temperature sealed | cool, dry storage |
| Shelf Life | 24 months unopened |

