QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS5-Region Domestic Shipping
What is Raloxifene?
Raloxifene (Evista — second-generation SERM (selective oestrogen receptor modulator)) is a Small molecule C₂₈H₂₇NO₄S, MW 473.6. Second-generation SERM with tissue-selective ER activity: agonist at bone (increases BMD) and cardiovascular receptors; antagonist at breast (no stimulation) and uterine ERα. FDA approved for osteoporosis treatment/prevention and breast cancer risk reduction. Different receptor conformation from tamoxifen.
Research Applications
Tissue-Selective ER Pharmacology
Bone agonist + breast antagonist — tissue selectivity research
Bone Density Research
BMD increase, osteoporosis prevention, osteoclast inhibition models
Breast Cancer Prevention
FDA-approved risk reduction reference compound — ER antagonism
vs Tamoxifen
First-generation vs second-generation SERM — tissue selectivity comparison
Cardiovascular ER Biology
ER-mediated lipid profile and cardiovascular effects
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 84449-90-1 |
| Molecular Formula | C₂₈H₂₇NO₄S, MW 473.6. |
| Identity | MS molecular weight confirmed — every batch |
| Peptide Type | Selective Estrogen Receptor Modulator (SERM) |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | As indicated by manufacturer |
