Orforglipron 12mg Tablets | 100-Count | GLP-1 Receptor Agonist

QSC Orforglipron (Oral non-peptide GLP-1R agonist) — ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.

✓ 99%+ Purity ✓ COA Available
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$310

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SKU: QSC-ORFORGLIPRON-12MG-100TAB
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QSC RESEARCH GRADE

≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS5-Region Domestic Shipping

What is Orforglipron?

Orforglipron (Oral non-peptide allosteric GLP-1R agonist) is a Small molecule (MW ~450, non-peptide). First non-peptide GLP-1R agonist approved (2025). Activates GLP-1R via allosteric (not orthosteric) binding — enabling oral bioavailability without peptide backbone. Biased agonism profile differs from peptide GLP-1R agonists. ATTAIN Phase 3: ~14.7% weight reduction at 36 weeks.

Research Applications

Allosteric GLP-1R Agonism

Allosteric vs orthosteric receptor binding comparison research

Oral Bioavailability

No injection stress confound — oral GLP-1R biology in rodent models

Biased Signalling

Small molecule vs peptide GLP-1R agonist downstream bias

Obesity Research

ATTAIN Phase 3 reference — 14.7% weight reduction at 36 weeks

vs Injectable GLP-1R

Mechanism and downstream signalling comparison

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 2211316-73-5
Identity MS molecular weight confirmed — every batch
Peptide Type Small Molecule GLP-1 Receptor Agonist
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months sealed

Certificate of Analysis (COA)

For the latest Certificate of Analysis (COA), please email us with your request.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA  ·  🇪🇺 EU  ·  🇬🇧 UK  ·  🇨🇦 Canada  ·  🇦🇺 Australia

Source: PubMed / NCBI  ·  Last 10 years  ·  Refreshed every 24 hours  ·  For research reference only — not clinical guidance.

⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION

QSC products are strictly for in vitro and in vivo laboratory research. Not intended for diagnostic, therapeutic, or personal use.

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Research Use Disclaimer

All QSC products are strictly for laboratory, scientific, and research use only. They are not for human consumption, medical treatment, diagnosis, or disease prevention.

By purchasing or using QSC products, you confirm:

  • You are a qualified researcher or acting under the supervision of one.
  • Products will only be used for legitimate research purposes.
  • Products are not evaluated by the FDA or any regulatory authority for human use.
  • You assume all responsibility for legal compliance, proper handling, and storage.
  • You meet the legal age requirement in your jurisdiction.
No Warranty: Products are sold “as is,” with no express or implied warranties regarding efficacy, safety, or suitability. Results in research may vary. QSC is not responsible for outcomes, interpretations, or conclusions drawn from any studies conducted using these products.
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General Safety & Handling

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Not for Human Use

These compounds are for research only. Any off-label, personal, or clinical use is strictly outside the intended scope of supply.

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PPE Required

Always use appropriate personal protective equipment (gloves, lab coat, eye protection) when handling peptides.

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Storage Compliance

Follow product-specific storage conditions to maintain identity, purity, and biological activity.

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Proper Disposal

Dispose of all materials in accordance with institutional biosafety, chemical waste, and hazardous material protocols.

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Verify Quality

Janoshik COAs are available on every product page. Verify batch identity (MS confirmed) and purity (≥99% HPLC) before use.

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Peptide Storage Guidelines

🌑 Light-protected💧 Low moisture🌡️ Stable temperature🔬 Sterile handling

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