QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS5-Region Domestic Shipping
What is Kisspeptin-10?
Kisspeptin-10 (Metastin (45-54) — GPR54/KISS1R agonist) is a 10-amino acid C-terminal kisspeptin fragment. C-terminal 10-amino acid fragment of kisspeptin-54 with full GPR54/KISS1R agonist potency — the minimal active fragment. GPR54 is the master GnRH pulse generator receptor in the hypothalamus, making kisspeptin-10 the physiological trigger for GnRH → LH → sex hormone cascade. Critical in puberty timing and reproductive cyclicity.
Research Applications
GPR54/KISS1R Pharmacology
Master GnRH pulse generator receptor activation and signalling
GnRH Pulse Research
Kisspeptin-GnRH neuron axis — LH pulsatility and frequency
Puberty Biology
Puberty timing, early/delayed puberty models, reproductive maturation
Sex Hormone Cascade
GnRH → LH → testosterone/oestrogen downstream research
vs Full-Length Kisspeptin
Minimal active fragment vs kisspeptin-54 — potency and duration
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | Not standardized (peptide fragment variant) |
| Molecular Formula | C₆₃H₈₃N₁₇O₁₄ |
| Peptide Type | Hypothalamic Signaling Peptide / GnRH Modulator |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | 24 months unopened |
