QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS5-Region Domestic Shipping
What is IGF-1 LR3?
IGF-1 LR3 (Long-Arg3 Insulin-Like Growth Factor-1) is a 83-amino acid IGF-1 analog (13-residue N-terminal extension). Long-acting IGF-1 analog with N-terminal 13-residue extension that reduces IGFBP binding by ~1000-fold, extending half-life to 20–30 hours vs 15 minutes for native IGF-1. Activates IGF-1R directly without requiring upstream GHR or hepatic IGF-1 production — IGFBP-resistant in serum-containing media.
Research Applications
IGF-1R Pharmacology
Direct IGF-1 receptor activation, PI3K-Akt-mTOR signalling
Extended Duration Studies
20–30hr half-life vs native IGF-1 (15min) — chronic exposure models
Serum Culture Research
IGFBP-resistant — suitable for serum-containing cell culture media
Muscle Anabolism
Protein synthesis, satellite cell activation, hypertrophy models
vs Native IGF-1
Isolate IGFBP-independent effects by comparison with native IGF-1
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 946870-92-4 |
| Molecular Formula | C₁₀₄H₁₇₄N₃₂O₃₀S |
| Peptide Type | Long-Acting Recombinant Peptide / IGF-1 Analog |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | 24 months unopened |
